2 . Clinical Management of Hiv - 1 Resistance
نویسندگان
چکیده
With variable degrees, drug-resistant HIV-1 is present in approximately 10%–20% of new infections in Western countries and in 60% of patients failing antiretroviral therapy. Non-nucleoside reverse transcriptase inhibitor mutations are the most common transmitted resistance mutations (4.5%-10%); NRTI (4.0%-4.5%) and PI mutations are less common (2.8%-3.4%)". Integrase mutations are uncommon but are being monitored in order to evaluate their evolution in the near future. Therefore, monitoring and overcoming HIV-1 drug resistance is crucial for guiding antiretroviral (ARV) treatment.
منابع مشابه
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